SOME CLONES I WILL DEFINITELY DIG (Acell with Hair Transplants!)
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June 07, 2010, 10:19 PM A little piece of science fiction turned close to fact coming at you….................. and its sitting on top of my head. Remember the article “Surgeons clone first transplanted hair” back in January? Well, one of those doctors was the same doctor who did both OMG and my hair transplants. The surprise I alluded to in another post????? Dr. Jerry Cooley, used Acell Matristem on both my donor and recipient areas. For the past year, he has primarily been using this novel discovery on special case patients only but, with my ultra fine scalp hair, below-average density donor area, and penchant for talking someone’s head off,..................... I got in! I know everybody interested in growing hair has heard of this enigmatic regenerative powder from the newsbreaking articles and special interview with Dr. Cooley on the Bald Truth: http://www.thebaldtruth.com/tag/acell/ Bu.t, as a refresher, Dr. Cooley, in Charlotte, NC and Dr. Hitzig, up in New York, are the only 2 hair transplant surgeons currently working with this new technology. Acell Matristem, is a breakthru regenerative dermatologic technology attracting much attention. This matrix has actually been shown to cause an amputated finger to grow back(pretty sick huh?). Although still in its experimental stages, this really is the 1st generation of “hair cloning”( or “hair multiplication”). So, again, what is Acell and what does it do? Acell, is a powder derived from urinary pig bladder matrix(that’s a mouthful). Acell’s actions work like this: When there is an injury in the body it can follow a regenerative pathway or a scar pathway. Acell, essentially recruits stem cells to come into the area where applied and form new blood vessels that regenerate the target tissue. Its best actions produce no scarring or dramatically less scarring and regenerated tissue, not to mention new follicles from existing follicles. One thing I really admire about Dr. Cooley, is that he is a scientist first and a surgeon second. This guy has been seriously engaged in furthering this field, since his beginnings less than 20 years ago. In fact, when he was in college, his research primarily focused on future technologies like hair cloning. I, personally, had been interested in getting a transplant with Dr. Cooley since 2003, and when I heard this news, it really sealed the deal, for me(okay OMG’s tp as well). Apparently Dr. Cooley, first started working with Acell last April and has used it in over a 100 patients so far, gathering a plethora of valuable data along the way. In October, Dr. Cooley, will present to his colleagues at IAHRS, all gathered data collected over the past year. Then, this trailblazing data will be reviewed and more than likely used by other surgeons all over the world. All I have to say is: Thanks…. Dr. Cooley for leading the way. Other surgeons,...........please suit up and get in the game! Overall, Dr. Cooley says he’s excited from the repair cases he has done and wants more people to be able to benefit from it. But, he is being cautiously optimistic at this point in discussing all the findings as this is still experimental stuff and he is waiting to process all his data. This past year has given Dr. Cooley great insight into Acell’s various uses and he is still taking notes. “The future definitely looks bright for this new technology.”, he says.
In regards to Acell, the question is how will I know if I grew any cloned hair? Dr. Cooley says “you wouldn’t be able to tell the difference between a cloned hair and regular hair.” To identify the cloned hair amongst regular transplanted hair, he actually plants the grafts in a certain pattern(2’s and 3’s, etc). Now if anything new shows up, outside this pattern, it is cloned hair . For me, this could mean not only a well healed, to totally regenerated, donor area, but a little extra up top as well. Dr. Cooley said he will tally all results of my transplant with Acell, in September when all the hair should be out. I will repost with pictures then. I might even do a closeup, outline of the pattern picture to be used as a marker and then circle the cloned hair. Then you will see the pattern and the cloned deviations. I sure am looking forward to results. In fact, anything in addition to what has been already transplanted will definitely be a nice bonus. To borrow Dr. Cooley’s words, the future really does look bright…... and I’m hooking this ship to a star with hair. |
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“A door within the fire creaks, suddenly flies open and a girl is standing there. Eyes alight with glowing hair all that fancy paints as fair, she takes her fan and throws it in the Lion’s Den.”
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 Editor Total Posts: 811 Member Since: |
[ # 1 ] June 08, 2010, 07:01 AM This is really big news, and I think a lot of people aren’t taking this in. Acell is being used in hair transplants, and not for just the donor area like everyone though would be the main use for it. Acell -when the transplanted follicle is dipped in it before it’s inserted into the scalp (I think that’s how it’s done)- is actually causing some hairs to CLONE at some point after it’s transplanted.
As some of you may or may not know, I made a special trip to Charlotte to bring DM5 the Post Laser Transplant Device and the Transplant Scar Device. I talked with Dr. Cooley about the results from Acell, and he said they ranged from normal to incredible. We don’t know if it’s dependent on the PERSON or what, and that’s what they are trying to figure out. Also, what I noted with my experience was replicated with DM5’s… we BOTH KEPT A SIGNIFICANT PORTION OF OUR HAIR AFTER THE TRANSPLANT IN THE FRONT OF OUR HEAD…
I’m going to document the case of LLLT with hair transplants in a video coming up very soon and you’ll know all of this like the back of your hand. Also, none of us involved -be it Cooley, me, DM5, or anyone I’ve mentioned this to- know why the hairs in the FRONT stay (they don’t go dormant and results in the “pohl pincus” phenomenon better than the ones in the back_. It must be related to bloodflow. -O.M.G. |
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Build your own Laser Helmet | Laser Brush | Laser Device at OverMachoGrande.com! The internet’s first, best, and biggest consumer advocate site on laser therapy for hair loss! It’s time to educate yourself about one of the greatest treatments in FORUM HISTORY… |
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Editor Total Posts: 811 Member Since: |
[ # 2 ] June 08, 2010, 07:57 AM Here is the Acell actually used in DM5’surgery…  Acell is being used experimentally in hair transplants for wound healing, scar reduction, and has been show to produce “cloned hairs” at some point during the healing process.
-O.M.G. |
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Build your own Laser Helmet | Laser Brush | Laser Device at OverMachoGrande.com! The internet’s first, best, and biggest consumer advocate site on laser therapy for hair loss! It’s time to educate yourself about one of the greatest treatments in FORUM HISTORY… |
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Member Total Posts: 191 Member Since: |
[ # 3 ] June 08, 2010, 07:07 PM He, he, he…........ Nice! All I remember about the stuff thru that soft, purple haze of narcotics that wrapped me in love was Dr. Cooley saying, ” Get some more Acell!” to one of his assistants. I couldn’t see anything but the tv in front of me. It could of been Ranch sauce or Texas Pete he was dippin my grafts in. But the best is, I’m sitting there in the chair all bombed out and giddy and I hear OMG’s voice in the background. Then all of a sudden he’s right by the chair asking Dr. Cooley if he can take over my surgery or something. Yikes! As layed back as I was, he could of been firing shotgun rounds past my ear telling Dr. Cooley to hand over the grafts, and I would of thought it all part of transplant. Good thing Dr. Cooley didn’t let OMG use his old fraternity tricks on me, I coulda come out looking like Mr. T. Anyway, that was awesome that you came up there dude! I mean the transplant was ridiculously easy with no real pain involved. But the Post Laser Transplant Healing Machine you brought made all the difference. ) 3 days post-transplant and very little to no redness in the recipient area…...................unheard of! Here are the pictures…..........
Finally, it was pretty awesome to get the blessings of The Grande Duke of Laser Hell on that most momentous of hairloss occasions! Thanks a bunch! |
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“A door within the fire creaks, suddenly flies open and a girl is standing there. Eyes alight with glowing hair all that fancy paints as fair, she takes her fan and throws it in the Lion’s Den.”
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Member Total Posts: 191 Member Since: |
[ # 4 ] June 08, 2010, 07:27 PM The way I understand it is it depends on the physiology of the person its being used on. That is why he has been so reserved about hyping it I think. I think we need to get him on at some point to talk about it at greater length. |
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“A door within the fire creaks, suddenly flies open and a girl is standing there. Eyes alight with glowing hair all that fancy paints as fair, she takes her fan and throws it in the Lion’s Den.”
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Editor Total Posts: 811 Member Since: |
[ # 5 ] June 08, 2010, 07:48 PM [BLACKLISTED word/name/company removed automatically]… Yeah, seems like it’s totally dependent on the person -who knows why! DM5… I’ve got a ton of footage in your hotel room with the stand device, etc. I wish I got more during the surgery, but it’s a fine line between “Type A Personality” and “Complete Dickhead”, and I though shoving the camera in everyone’s faces during surgery would put me more in the latter category! lol… Yeah, you know… I’ve started to realize that when I’m in public scenarios like that as “OverMachoGrande” instead of “John Christian”, I often stroll in and inadvertantly start to take on the larger than life personality of Joe Pinner, the long-time weatherman from my hometown! Ha ha ha! He even had sort of a “Krusty the Clown” type of local kids morning show back in the 80’s (the “Mr. Knowzit Show”)! He was a big ham on local commercials, too. It’s funny, we’re all influenced by people like that and sometimes we don’t even know it. Anyway, you’ll see the footage I’ve got on the video. -O.M.G. |
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Build your own Laser Helmet | Laser Brush | Laser Device at OverMachoGrande.com! The internet’s first, best, and biggest consumer advocate site on laser therapy for hair loss! It’s time to educate yourself about one of the greatest treatments in FORUM HISTORY… |
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Member Total Posts: 191 Member Since: |
[ # 6 ] June 08, 2010, 09:00 PM I know what ya mean, I think I have a couple myself. Yeah you ought to show them what the room setup looks like.
Almost forgot that when I went back to my hotel room after the transplant, OMG had setup the Post Laser Tranplant Healing Device comfortably in front of the TV. and there was a cigar resting on the desk close by. I was blown away. I thought, everybody ought to be so lucky to have his “Laserness” near when they have a hair transplant. I mean having OMG at your transplant has got to be like having the Pope at your wedding(too cool!).
Let me know when you need the Post Transplant Device for videos and whatever else and I will get it on its way. I am just starting to use the laser helmet again but being cautious as it is a sensitive area in the front. It’s like I use the laser helmet once and then freak cause there is some soreness around the grafted area after the session so I end up going back to using the stand. But whenever you need it I will be ready to make the final leap back to the helmet. |
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“A door within the fire creaks, suddenly flies open and a girl is standing there. Eyes alight with glowing hair all that fancy paints as fair, she takes her fan and throws it in the Lion’s Den.”
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 Editor Total Posts: 508 Member Since: |
[ # 8 ] June 14, 2010, 02:04 AM Can someone here tell me why this isn’t a news article on the FRONT PAGE? C’mon guys…! DM5—talk to OMG about getting article posting privileges. I’ll help you with HTML formatting and what-not if you’d like. |
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Editor Total Posts: 811 Member Since: |
[ # 9 ] June 14, 2010, 04:03 PM It’s not on the front page the same reason the other 400 articles aren’t! Don’t worry… we’ve talked to Dr. Cooley about this. It will happen. -O.M.G. |
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Build your own Laser Helmet | Laser Brush | Laser Device at OverMachoGrande.com! The internet’s first, best, and biggest consumer advocate site on laser therapy for hair loss! It’s time to educate yourself about one of the greatest treatments in FORUM HISTORY… |
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New Member Total Posts: 2 Member Since: |
[ # 10 ] July 04, 2010, 05:53 AM Anything new regarding old punch/plug repair using Acell? Also stay away from Hitzig…...his office was the one that scared me for life IN 97! |
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New Member Total Posts: 2 Member Since: |
[ # 11 ] July 04, 2010, 09:58 AM just found on the net…... Before being able to regenerate tissue, they have to stop the mechanism of scarring. According to Atala’s law: “It all leads back to the scar. Eliminate the scar and you can regenerate tissue, even digits and complex organs. You don’t eliminate the scar you cannot regenerate tissue.” I think most of you would know that if you operate on a fetus within the first three months of pregnancy in humans, you would get completely no scarring. Therefore, humans do have an innate ability to heal completely without scarring. A non-denatured extra-cellular matrix would be capable of regenerating wounds totally without scarring. Like ECM, and hyaluronic acid, decorin (a component of ECM) has been studied and a lot of products are being designed on its micro mechanisms of action. In wounds it is known there is a race between scarring and regeneration. Decorin stops scarring by keeping the fibrils slender. Decorin plays a part in non denatured ECM healing. (Question,would decorin salvage slightly denatured ECM?). It is the factor that tells the ECM I’m not injured, do not scar, and let the ECM be normally woven without the over expression of collagen on the fibers. Decorin completely hinders the scarring response which enables intercellular tissues to crawl up the ECM to win the race. Decorin is a normal human protein, and naturally occurring extracellular matrix protein, a proteoglycan that has a regulatory effect mechanism over TGF-?, and whilst inhibiting TGF-B it increases the expression of key MMPs that break down the ECM. Evidence shows that decorin is required for the proper assembly of collagenous matrices quote: “Decorin-treated wounds have been found to exhibit essentially no detectable scarring compared to control wounds not treated with decorin. The TGF-?-induced scarring process has been shown to be unique to adults and third trimester human fetuses, but is essentially absent in fetuses during the first two trimesters. The absence of scarring in fetal wounds has been correlated with the absence of TGF? in the wound bed. In contrast, the wound bed of adult tissue is heavily deposited with TGF-? and the fully healed wound is replaced by a reddened, furrowed scar containing extensively fibrous, collagenous matrix. The decorin-treated wounds were histologically normal and resembled fetal wounds in the first two trimesters.” source: http://www.freepatentsonline.com/6509314.html It is clearly understood that scarring occurs due to collagen over expression which dense up the collagen fibers in ECM which blocks pathways. In 2006 it was officially announced in a publication that this ECM protein can completely inhibit scarring by inhibiting collagen overexpression. Allowing our intercellular tissues to grow through the ECM just like what happens in scar free healing. Recombinant Human Decorin Inhibits Cell Proliferation and Downregulates TGF-β1 Production in Keloid Fibroblasts VOLUME: 18 PUBLICATION DATE: Aug 01 2006 At decorin concentrations of 100 nM and 200 nM, fibroblast proliferation was completely inhibited (P < 0.001), and the expected temporal increase in absorbance units was completely abolished, indicating a static population http://www.woundsresearch.com/article/6067 06-03-2009, 08:19 PM Are you making an argument or engaging in hopeful, if not exactly wishful, thinking? Look, regeneration using an earlier ECM called alloderm: ( warning graphic ) http://www.eplasty.com/index.p…mid=36§=15 Look at this guy’s kunckles showing his bones. After treatment, his wound regenerated leaving a normal hand. and using the acell ECM to regenerate a full thickness dermal wound of a feline( Literally exposing his bone ) http://www.acellvet.com/vetcases/lucille.php FYI, im not promoting any product but im just saying by looking at those pictures, if we logically think we already have the ability to stop scarring, but everything is under the radar, stopping scarring itself is already a big medical revolution. |
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