hopeful19

New Member

Total Posts: 15

Member Since:
February 2010

March 14, 2010, 09:22 PM

Is adenosine of any use?
I ask because folica has Dermenodex on sale for $11

http://www.folica.com/Dermenodex_Thin_d3246.html

Immortal Hair

Editor

Total Posts: 117

Member Since:
January 2010

[ # 1 ]

March 15, 2010, 12:04 PM

J Dermatol. 2008 Dec;35(12):763-7.
Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss: a pilot, double-blind, randomized, placebo-controlled trial.

Oura H, Iino M, Nakazawa Y, Tajima M, Ideta R, Nakaya Y, Arase S, Kishimoto J.

Department of Dermatology, School of Medicine, University of Tokushima, Tokushima, Japan.

Adenosine upregulates the expression of vascular endothelial growth factor and fibroblast growth factor-7 in cultured dermal papilla cells. It has been shown that, in Japanese men, adenosine improves androgenetic alopecia due to the thickening of thin hair due to hair follicle miniaturization. To investigate the efficacy and safety of adenosine treatment to improve hair loss in women, 30 Japanese women with female pattern hair loss were recruited for this double-blind, randomized, placebo-controlled study. Volunteers used either 0.75% adenosine lotion or a placebo lotion topically twice daily for 12 months. Efficacy was evaluated by dermatologists and by investigators and in phototrichograms. As a result, adenosine was significantly superior to the placebo according to assessments by dermatologists and investigators and by self-assessments. Adenosine significantly increased the anagen hair growth rate and the thick hair rate. No side-effects were encountered during the trial. Adenosine improved hair loss in Japanese women by stimulating hair growth and by thickening hair shafts. Adenosine is useful for treating female pattern hair loss in women as well as androgenetic alopecia in men.

Nidhogge

Editor

Total Posts: 505

Member Since:
January 2010

[ # 2 ]

March 20, 2010, 02:19 PM

Definitely is, in fact, I made it one of the actives in “HairGen” when formulating it!

J87

Member

Total Posts: 65

Member Since:
April 2010

[ # 3 ]

April 07, 2010, 01:09 AM

Anyone know how much adenosine is too much? Sinere only put like 1.5% in their topicals, claiming that more would have adverse effects. Dermenodex contains 3%, would apply twice daily be overkill, especially if you also use a laser helmet?

NDFAN

Member

Total Posts: 28

Member Since:
March 2010

[ # 4 ]

April 07, 2010, 08:12 AM

Hello Nidhogge,
Where do I find your product Hairgen? What is the cost? ingredients?

Thanks

Socrates

Member

Total Posts: 25

Member Since:
January 2010

[ # 5 ]

April 07, 2010, 09:35 AM

How have responded to HairGen so far Nidhogge ?

J87

Member

Total Posts: 65

Member Since:
April 2010

[ # 6 ]

April 07, 2010, 01:27 PM

HairGen isn’t out yet, they’re still working on it. In the meantime I ordered 3 bottles of dermenodex, not sure if I should only apply it once per day or twice.

Chore Boy

Member

Total Posts: 39

Member Since:
January 2010

[ # 7 ]

April 08, 2010, 12:26 PM

Who knows… Dermenodex may be a buffered solution but, if I’m not mistaken, ATP is unstable outside of one and readily converts back to its precursors.