Adenosine
 New Member Total Posts: 13 Member Since: |
March 14, 2010, 10:22 PM Is adenosine of any use? |
 Editor Total Posts: 89 Member Since: |
[ # 1 ] March 15, 2010, 01:04 PM J Dermatol. 2008 Dec;35(12):763-7. Department of Dermatology, School of Medicine, University of Tokushima, Tokushima, Japan. Adenosine upregulates the expression of vascular endothelial growth factor and fibroblast growth factor-7 in cultured dermal papilla cells. It has been shown that, in Japanese men, adenosine improves androgenetic alopecia due to the thickening of thin hair due to hair follicle miniaturization. To investigate the efficacy and safety of adenosine treatment to improve hair loss in women, 30 Japanese women with female pattern hair loss were recruited for this double-blind, randomized, placebo-controlled study. Volunteers used either 0.75% adenosine lotion or a placebo lotion topically twice daily for 12 months. Efficacy was evaluated by dermatologists and by investigators and in phototrichograms. As a result, adenosine was significantly superior to the placebo according to assessments by dermatologists and investigators and by self-assessments. Adenosine significantly increased the anagen hair growth rate and the thick hair rate. No side-effects were encountered during the trial. Adenosine improved hair loss in Japanese women by stimulating hair growth and by thickening hair shafts. Adenosine is useful for treating female pattern hair loss in women as well as androgenetic alopecia in men.
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Member Total Posts: 21 Member Since: |
[ # 3 ] April 07, 2010, 02:09 AM Anyone know how much adenosine is too much? Sinere only put like 1.5% in their topicals, claiming that more would have adverse effects. Dermenodex contains 3%, would apply twice daily be overkill, especially if you also use a laser helmet? |
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