Estrogen, Aromatase & Insulin

By Immortal Hair, January 16th, 2010, 6:33 pm

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Estrogen, Aromatase & Insulin

The older the male, the greater the possibility of elevated aromatase enzyme expression.  Enlarged prostate, balding, insulin resistance, enlarged breasts, abdominal obesity have a common link, which is excess aromatization.  Many men who are checked for low testosterone and then are subsequently given testosterone shots, creams or gel may not get much better unless their aromatization expression is checked.

What good is testosterone supplementation if most of it is being converted into estrogen?  More importantly, how does one check for this?  The answer is testosterone to estrogen ratio.

Looking at your lab tests, make note if your testosterone is below the mid-range while also checking to see if your estrogen is above the mid-range.  The degree of concern of course is how close to the low end range is testosterone relative to how close the estrogen level is toward the top of its range.  If this tendency is shown, elevated aromatization is likely present.  Furthermore, and with a high confidence level you’re also insulin resistant.

What to do?  Identify your nutritional or metabolic type, but regardless of this, laying off refined grains, starches, sugars, vegetable oils, hydrogenated oils, pre-packaged foods is a step in the right direction.  Next, improving glucose metabolism and optimizing a balance of healthy gut microflora is very important.  Checking your thyroid and/or iodine intake.  Some of estrogen’s adverse effects can be contained with sufficent iodine intake.  Heightened levels of estrogen can increase prolactin and also induce hypothyroidism.  Beware of anti-anxiety and anti-depressant medication, since many of these increase prolactin levels, and suppress the thyroid all leading to increased estrogen levels.

Supplements for this would include, Vitamin K2, a very good probiotic, Spruce Lignans (7-hydroxymatairesinol), iodine, Curcumin, Lipoic Acid, Ecklonia Cava, Resveratrol, Zinc, Omega-3 fatty acids, Nettle using the methanolic extract only, and passionflower.

Supplements such as these can be ordered at a reduced cost at http://www.iherb.com
To save $5 dollars off the initial order, use code “HIL335

Brian Simonis

Brian Simonis is an Orthomolecular medicine researcher in all health related aspects, specializing in anti-aging medicine, degenerative disease prevention and with great emphasis on hair loss pathology and treatment.

Having worked in one of the largest integrative medicine treatment centers in the Northern hemisphere, it has afforded him the opportunity to spend thousands of hours with patients and reviewing their medical histories, working with like-minded, pioneering physicians and seeing the over-all big picture of natural, health medicine.

Furthermore, he serves as an independent health consultant, specializing in natural hair loss treatment.


COMMENTS (10)


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Nidhogge

Nidhogge

Editor

January 18th, 2010, 03:09 AM

Fantastic entry, Brian!  One question though… you mentioned as one of the solutions to “Identify your nutritional or metabolic type.”  Do you have any resources that you wouldn’t mind sharing that would allow people to find out what metabolic type they are?

Immortal Hair

Immortal Hair

Editor

January 18th, 2010, 02:05 PM

Dan - One such site to consult is http://www.bloodph.com/

However, it’s a little pricey. Alternatively, there are some other ways to determine one’s correct diet. On a similar premise, there is the ancestral diet, which is to say that those who have lived in their indigenous communities, free of processed food can rely on their native diets as a shining example of ideal food staples.

Of course, quite a large number of people no longer consume their native diets, and when a mixture of races play a role, the picture becomes even less clear.

Generally speaking, there is no such thing as a “one size fits all diet.”

According to the author of The Metabolic Typing Diet, William Wolcott, individual metabolism relates to the autonomic nervous system (ANS).  The autonomic nervous system is split into two components, the Sympathetic and the Parasympathetic. The Sympathetic involves stress hormones and is acidifying.  The Parasympathetic involves digestion and is alkalizing.

We are often told that alkalizing the body is the way of health.  It’s not quite that simple.  Have you ever wondered why some individuals thrive on high carbohydrate, low fat diets, while others do better on a low carbohydrate, high fat diet?  What about types of protein?  A high fat, high meat diet can either make or break a person, it entirely depends on whether they are Sympathetic or Parasympathetic dominant.  In other words, what is your individual metabolic type?

According to your metabolic type, the balance of your pH depends on which side of the autonomic nervous system you stand; Sympathetic or Parasympathetic.  Let’s say you fall into the Parasympathetic category or are Parasympathetic dominant.  It means you are already alkaline, and to eat a vegetarian based diet will tip the scales towards over alkalinity. 

Conversely, if you are Sympathetic dominant, your acidity will balanced out with a vegetarian based diet.  Determining what type you are will make all the difference in your overall health.

How does one determine their metabolic type?  The first indication is by way of your Triglycerides (blood fats) during a fasting blood test.  A reading above 80 indicates potential excess insulin activity.  If this is you, you’re likely to be Parasympathetic dominant, which means you easily convert your carbohydrates into fats.  Naturally, a low carbohydrate diet would suit you best.  For those with a triglyceride reading below 80, a metabolic-typing test
would need to be run to determine where you stand.

It is not surprising that Parasympathetic types usually come fashioned with a strong digestive system, allowing them to eat flesh foods, while Sympathetic types do much better on vegetables and whole grains.

While the majority of us have a dominant branch of either the Sympathetic or Parasympathetic, others have an equal balance and they require a variety of food types. 

Finally, there is another consideration that involves the impact of processed food. Food that has been refined, processed and fortified with additives significantly changes the metabolism. Many processed grain foods contain added inorganic iron, monosodium glutamate (MSG) and/or their synonyms, such as sodium glutamate, L-glutamic acid, monosodium salt, Hydrolyzed vegetable protein, Autolyzed yeast, Whey protein and others.

These additives can generate lipid peroxides and other free radicals, causing noticeable inflammation in the scalp. Further, there are lectins found in wheat and other grains and legumes that can create a lot of inflammation. The question is, how do these foods effect an individual?

If one avoids processed food all together, then determining what their ideal diet is can be made far more easily.


_________________
http://www.immortalhair.org/mycurrentregimen.htm

Now available for consultation (hair and/or health)
http://www.immortalhair.org/consultation.htm

Silverlin

Silverlin

Member

January 19th, 2010, 06:02 AM

“Fantastic entry, Brian!” - I second that! Oh and sweet avatar Nid!

You guys have created like a super league, sort of like the “avengers” of hair loss, lol. Its only a matter of WHEN(not IF)the enigma that is hair loss is conquered(getting so close). And the damn FDA and powers that be won’t be able to do a damn thing to stop us!

The Zix Creator

The Zix Creator

Editor

January 21st, 2010, 02:22 AM

Good article. I know this is kind of off the wall but what would be the results if someone started exercising regularly? We know exercise will increase insulin production and lower blood sugar.

What affect would exercise have on our testosterone to estrogen ratio?

Nidhogge

Nidhogge

Editor

January 21st, 2010, 12:06 PM

Silverlin—

Thanks man!  When I saw this avatar, I thought man, this is PERFECT, haha.  And, I like that—“avengers” of hair loss. wink

Zix—

Exercising regularly increases testosterone, and lowers estrogen.  Couple that with a decent, anti-estrogenic diet, and you’ll sure as heck look and feel a lot better about life.

BaldbeGone

BaldbeGone

Member

January 31st, 2010, 03:44 PM

“Exercising regularly increases testosterone, and lowers estrogen.  Couple that with a decent, anti-estrogenic diet, and you’ll sure as heck look and feel a lot better about life”

Hey Nid…does this include weightlifting, calisthenics, or cardio?


Sure, shit happens...but so does good shit!

Nidhogge

Nidhogge

Editor

January 31st, 2010, 05:47 PM

I speak mainly from a weight lifter’s perspective, and while I’d like to include cardio and calisthenics, I honeestly just don’t know nearly as much about the effects that they have on our hormone profiles.  Generally, if I’m not being a slug, I try to incorporate a lot of drop setting/super setting into my weight lifting routines to keep my heart rate and caloric output high.

Gregsmom48

Member

November 28th, 2011, 08:59 AM

Hi there!

Finally got around to reading this excellent piece. Very interested in how all this affects me as a female. FWIW I am a breast cancer survivor and as such I am on femara, which is an aromatase inhibitor. I know that this had a bad effect on my hair, which OMG’s helmet, as well as time, helped to clear up, as my hair “got used” to it—not to say that the helmet didn’t do wonders.

Please advise

warmly
Gregsmom48 aka Hope

Immortal Hair

Immortal Hair

Editor

November 28th, 2011, 08:37 PM

Gregsmom48 - Yes, blocking aromatase can lead to hair loss. Alopecia is of course a listed potential side-effect of taking femara. The good news is that iodine can be taken instead of femara. Iodine also blocks estrogen.

It can take several months of high-dose iodine therapy in order to saturate the tissue, so if this were to be done hypothetically, one would want do go off of femara or other aromotase inhibitor only after an iodine loading tests shows > 90% excretion level.

Some back ground info about iodine which is somewhat relevant to this topic.

http://www.scribd.com/doc/1959949/IODINE-Solution-to-Healthproblems

Also, bear in mind that in estrogen sensitive breast cancer, there is always—without known exception to have a high bromide or other goitrogen level and a simultaneous low iodine level in breast tissue.

Iodine is stimulates apoptosis in breast tissue when it reaches levels of saturation. This requires a gradual building up of doses which are hundreds of times above the RDA (Rats drugs and assumptions level).

Other considerations, almost all breast cancer patients have a tooth on a specific meridian line where there is either a cavitation, root canal or infected crown or tooth. An infection of type can “seed” it.

Here’s more info about iodine within an article on metal detox, which by the way is a very important consideration for keeping healthy cells in check.

http://healthyfixx.com/plan/5/heavy-metal-detox

http://healthyfixx.com/plan/6/fixxing-your-thyroid

 


_________________
http://www.immortalhair.org/mycurrentregimen.htm

Now available for consultation (hair and/or health)
http://www.immortalhair.org/consultation.htm

Gregsmom48

Member

December 01st, 2011, 08:45 AM

Thanks, Immortal Hair

I will discuss with my alternative care Doc next I see him.

In light of this, OMG’s helmet is even more awesome as my hair has returned excellently from both chemo AND femara.

warmly,
h

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